LAII 2020 Presentations for Download
Wim Hennink – Utrecht University
Diels-Alder in Situ Forming Hydrogel for Sustained Intraocular Release of Bevacizumab
Frederic Dargelas – DelSiTech
Parenteral Delivery of Therapeutic Proteins Using Biodegradable Silica
Tom Tice – Evonik
The APIs of LAIIs (available by request, please email laii@ddelabs.com)
Jukka Rantanen – University of Copenhagen
Towards Commercial Scale Production of Quality by Design (QbD) Based Nanomedicine
Mark Prausnitz – Georgia Institute of Technology
Microneedle Device for Long-Acting Contraceptive Hormone
David Friend – Daré Bioscience, Inc.
An Innovative Long-Acting Implant for Contraception
Charles Flexner – Johns Hopkins University
Novel Approaches to HIV Treatment and Prevention Using Long-Acting Drug Delivery
Tejal Desai – University of California, San Francisco
Nanostructured Materials for Long-Acting Biologic Delivery
Tassos Nicolaou – Delpor, Inc.
Prozor Technology and the Potential for Once-Yearly Therapies
Jon Pokorski – University of California, San Diego
Melt Processing of Functional Protein/Polymer Blends
Karsten Mäder – Martin Luther University, Halle-Wittenberg
Noninvasive In Vitro and In Vivo Characterization of Biodegradable Parenteral Depot Formulations
Sheng Qi – University of East Anglia
3D Printing of Personalized Long-Acting Pharmaceutical Implants: Conceptual Analysis and Printing Design
Wim Jiskoot – Leiden University
Long-Acting Injectables & Implantables: Immunogenicity Concerns
Steve Schwendeman – University of Michigan
A Cage Implant to Study Drug Release from Microspheres In Vivo
Viera Lukacova – Simulations Plus, Inc.
What Does it Take to Develop a PBPK Model that Mimics In Vivo Behavior of LAIs
Sponsored Presentations
Jeff Haley – Celanese Engineered Materials
Ethylene-Vinyl Acetate Polymers for Long-Acting Dosage Forms
Global Health Panel – MedinCell and Medicines Patent Pool
Opportunities to Address Global Health Challenges With Long-Acting Technologies
Robert Lee – Lubrizol Life Science
Overcoming Development Challenges for Long-Acting Injectables & Implantables
Event Photos
Final Agenda
Thursday, Feb. 6, 2020
| 8:00 a.m. - 9:00 a.m. | Breakfast |
| 9:00 a.m. - 9:10 a.m. | Welcome and Opening Remarks |
| 9:10 a.m. - 9:50 a.m. |
 Wim Hennink
- Utrecht University
Diels-Alder in Situ Forming Hydrogel for Sustained Intraocular Release of Bevacizumab View Abstract |
| 9:50 a.m. - 10:30 a.m. |
 Frederic Dargelas
- DelSiTech
Parenteral Delivery of Therapeutic Proteins Using Biodegradable Silica View AbstractDownload Presentation |
| 10:30 a.m. - 11:00 a.m. | Networking Break & Poster Viewing |
| 11:00 a.m. - 11:40 a.m. |
 Ved Srivastava
- Intarcia Therapeutics
Patient-Centric Peptide Drug Design and Sustain Delivery for Metabolic Disease View Abstract |
| 11:40 a.m. - 12:20 p.m. |
 Raj Patel
- Titan Pharmaceuticals
Probuphine Product Development View Abstract |
| 12:20 p.m. - 1:20 p.m. | Lunch Sponsored by Celanese (Chronicle Room) |
| 1:20 p.m. - 2:00 p.m. |
 Tom Tice
- Evonik
The APIs of LAIIs View Abstract |
| 2:00 p.m. - 2:40 p.m. |
 Jukka Rantanen
- University of Copenhagen
Towards Commercial Scale Production of Quality by Design (QbD) Based Nanomedicine View Abstract |
| 2:40 p.m. - 3:20 p.m. |
 Joyce Hotz
- AstraZeneca
Scale Up of Bydureon View Abstract |
| 3:20 p.m. - 3:50 p.m. | Networking Break & Poster Viewing |
| 3:50 p.m. - 4:30 p.m. |
 Mark Prausnitz
- Georgia Institute of Technology
Microneedle Device for Long-Acting Contraceptive Hormone View AbstractDownload Presentation |
| 4:30 p.m. - 5:10 p.m. |
 David Friend
- Daré Bioscience, Inc.
An Innovative Long-Acting Implant for Contraception View AbstractDownload Presentation |
| 5:10 p.m. - 5:50 p.m. |
 Charles Flexner
- Johns Hopkins University
Novel Approaches to HIV Treatment and Prevention using Long-Acting Drug Delivery View Abstract |
| 5:50 p.m. - 6:00 p.m. | Day One Closing Remarks |
| 6:00 p.m. - 8:00 p.m. | Dinner and Panel Discussion Sponsored by MedinCell and Medicines Patent Pool (Americana Ballroom) |
Friday, Feb. 7, 2020
| 8:00 a.m. - 9:00 a.m. | Breakfast |
| 9:00 a.m. - 9:10 a.m. | Welcome and Opening Remarks |
| 9:10 a.m. - 9:50 a.m. |
 Tejal Desai
- University of California, San Francisco
Nanostructured Materials for Long Acting Biologic Delivery View Abstract |
| 9:50 a.m. - 10:30 a.m. |
 Tassos Nicolaou
- Delpor
Prozor Technology and the Potential for Once-Yearly Therapies View Abstract |
| 10:30 a.m. - 11:00 a.m. | Networking Break & Poster Viewing |
| 11:00 a.m. - 11:40 a.m. |
 Jon Pokorski
- University of California, San Diego
Melt Processing of Functional Protein/Polymer Blends View AbstractDownload Presentation |
| 11:40 a.m. - 12:20 p.m. |
 Hongwen Rivers
- Allergan
To Develop Long-Acting Complex Dosage Forms of Biologics for the Eye: Opportunities and Challenges View Abstract |
| 12:20 p.m. - 1:20 p.m. | Lunch Sponsored by Lubrizol Life Science (Chronicle Room) |
| 1:20 p.m. - 2:00 p.m. |
 Karsten Mäder
- Martin Luther University Halle-Wittenberg
Noninvasive In Vitro and In Vivo Characterization of Biodegradable Parenteral Depot Formulations View Abstract |
| 2:00 p.m. - 2:40 p.m. |
 Sheng Qi
- University of East Anglia
3D Printing of Personalised Long-Acting Pharmaceutical Implants: Conceptual Analysis and Printing Design View Abstract |
| 2:40 p.m. - 3:00 p.m. | Networking Break & Poster Viewing |
| 3:00 p.m. - 3:40 p.m. |
 Wim Jiskoot
- Leiden University
Long-Acting Injectables & Implantables: Immunogenicity Concerns View Abstract |
| 3:40 p.m. - 4:20 p.m. |
 Omid Veiseh
- William Marsh Rice University
Immune Modulatory Biomaterials for Cell-Based Therapeutics View Abstract |
| 4:20 p.m. - 4:40 p.m. | Networking Break & Poster Viewing |
| 4:40 p.m. - 5:20 p.m. |
 Steve Schwendeman
- University of Michigan
A Cage Implant to Study Drug Release from Microspheres In Vivo View Abstract |
| 5:20 p.m. - 6:00 p.m. |
 Viera Lukacova
- Simulations Plus, Inc.
What Does it Take to Develop a PBPK Model that Mimics In Vivo Behavior of LAIs View Abstract |
| 6:00 p.m. - 6:40 p.m. |
 Diane Burgess
- University of Connecticut
Development of IVIVCs for Complex Parenteral Products View Abstract |
| 6:40 p.m. - 6:50 p.m. | Day Two Closing Remarks |
Sponsored Programming
Thursday Lunch | Sponsored by Celanese
12:20 p.m. – 1:20 p.m.
Jeff Haley – Celanese Engineered Materials
Ethylene-Vinyl Acetate Polymers for Long-Acting Dosage Forms
Friday Lunch | Sponsored by Lubrizol Life Science
12:20 p.m. – 1:20 p.m.
Robert Lee – Lubrizol Life Science
Overcoming Development Challenges for Long-Acting Injectables & Implantables
View Abstract
Thursday Dinner and Global Health Panel Discussion | Sponsored by MedinCell & Medicines Patent Pool
6:30 p.m. – 8:30 p.m.
- Charles Flexner (chair) – Long-Acting/Extended Release Antiretroviral Resource Program (LEAP)
- Carmen Pérez Casas – Unitaid
- Dennis Lee – The Bill & Melinda Gates Foundation
- Andrew Owen – University of Liverpool
- Rodney Ho – University of Washington
- Stephanie Barrett – Merck
- Christophe Roberge – MedinCell
- Esteban Burrone – Medicines Patent Pool
Thank You To Our LAII 2020 Sponsors
Gold-Level Sponsors
Silver-Level Sponsor
Exhibiting Sponsors
Sponsorship Opportunities
LAII 2021 offers several sponsorship packages for companies looking for access to our attendees and unique brand exposure. For more information on sponsorship opportunities for next year’s meeting, please connect laii@ddelabs.com.
Thank You to the 2020 Planning Committee
Nima Akhavein, GSK
Maria Josè Alonso, USC
Rene Holm, Janssen
Julius Korley, University of Delaware
Laxma Reddy, Drug Delivery Experts
Chris Rhodes, Drug Delivery Experts
Steve Schwendeman, University of Michigan
An Vermeulen, Janssen
Dennis Lee, Gates Foundation
LAII 2020 Accepted Poster Presentations
Self-Administered Biodegradable Microneedle Patches for Sustained Release of Etonogestrel
By: Derek Jang+, Jonathan Chen+, Jie Tang, Richard Terry, Steve Schwendeman, Mark R. Prausnitz (Georgia Institute of Technology)
Probing Particle-Stabilizer Interactions in Long-Acting Parenteral Formulations through Novel In Vitro Methods and Spectroscopic Techniques
By: Nathan Rudd (Merck & Co., Inc.)
Noninvasive Replenishment of Drug Depots In Vivo
By: Yevgeny Brudno (UNC – Chapel Hill and NC State – Raleigh)
GQDs and MnFe2O3 Decorated Molybdenum Nanosheets for sub cellular Targeted Dual Mode Photodynamic Therapy (PDT)/Photothermal Therapy (PTT) of Glioblastoma
By: Abhijeet Pandey (Manipal College of Pharmaceutical Sciences)
Long-Acting Implantables Using Surface-eroding Elastomers Sustain Zero-order, Multi-month release
By: Stephanie Reed (Secant)
Micro-imaging Based Characterization and Prediction of Long-Acting Parenteral
By: Shawn Zhang (DigiM), Karthik Nagapudi (Genentech)
Novel Long-Acting Injectable Photocrosslinked Drug Delivery Systems for the Treatment of Ocular Diseases
By: Raj Thakur (Re-Vana Therapeutics)
Presentation & Poster Abstract Submission for LAII 2021
We are currently accepting presentation & poster abstracts for next year's meeting. Please leave your name, email, your talk/poster title, and abstract below:
