LAII 2020 Program Book Now Available

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LAII 2020 Presentations for Download

Wim Hennink – Utrecht University
Diels-Alder in Situ Forming Hydrogel for Sustained Intraocular Release of Bevacizumab

Frederic Dargelas – DelSiTech
Parenteral Delivery of Therapeutic Proteins Using Biodegradable Silica

Tom Tice Evonik
The APIs of LAIIs (available by request, please email laii@ddelabs.com)

Jukka Rantanen University of Copenhagen
Towards Commercial Scale Production of Quality by Design (QbD) Based Nanomedicine

Mark Prausnitz – Georgia Institute of Technology
Microneedle Device for Long-Acting Contraceptive Hormone

David Friend – Daré Bioscience, Inc.
An Innovative Long-Acting Implant for Contraception

Charles Flexner – Johns Hopkins University
Novel Approaches to HIV Treatment and Prevention Using Long-Acting Drug Delivery

Tejal Desai  – University of California, San Francisco
Nanostructured Materials for Long-Acting Biologic Delivery

Tassos Nicolaou – Delpor, Inc.
Prozor Technology and the Potential for Once-Yearly Therapies

Jon Pokorski – University of California, San Diego
Melt Processing of Functional Protein/Polymer Blends

Karsten Mäder – Martin Luther University, Halle-Wittenberg
Noninvasive In Vitro and In Vivo Characterization of Biodegradable Parenteral Depot Formulations

Sheng Qi – University of East Anglia
3D Printing of Personalized Long-Acting Pharmaceutical Implants: Conceptual Analysis and Printing Design

Wim Jiskoot – Leiden University
Long-Acting Injectables & Implantables: Immunogenicity Concerns

Steve Schwendeman – University of Michigan
A Cage Implant to Study Drug Release from Microspheres In Vivo

Viera Lukacova – Simulations Plus, Inc.
What Does it Take to Develop a PBPK Model that Mimics In Vivo Behavior of LAIs

Sponsored Presentations

Jeff Haley – Celanese Engineered Materials
Ethylene-Vinyl Acetate Polymers for Long-Acting Dosage Forms

Global Health Panel – MedinCell and Medicines Patent Pool
Opportunities to Address Global Health Challenges With Long-Acting Technologies

Robert Lee – Lubrizol Life Science
Overcoming Development Challenges for Long-Acting Injectables & Implantables

Event Photos

Final Agenda

Thursday, Feb. 6, 2020

8:00 a.m. - 9:00 a.m. Breakfast
9:00 a.m. - 9:10 a.m. Welcome and Opening Remarks
9:10 a.m. - 9:50 a.m. Wim Hennink - Utrecht University

Diels-Alder in Situ Forming Hydrogel for Sustained Intraocular Release of Bevacizumab

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9:50 a.m. - 10:30 a.m. Frederic Dargelas - DelSiTech

Parenteral Delivery of Therapeutic Proteins Using Biodegradable Silica

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10:30 a.m. - 11:00 a.m. Networking Break & Poster Viewing
11:00 a.m. - 11:40 a.m. Ved Srivastava - Intarcia Therapeutics

Patient-Centric Peptide Drug Design and Sustain Delivery for Metabolic Disease

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11:40 a.m. - 12:20 p.m. Raj Patel - Titan Pharmaceuticals

Probuphine Product Development

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12:20 p.m. - 1:20 p.m. Lunch Sponsored by Celanese (Chronicle Room)
1:20 p.m. - 2:00 p.m. Tom Tice - Evonik

The APIs of LAIIs

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2:00 p.m. - 2:40 p.m. Jukka Rantanen - University of Copenhagen

Towards Commercial Scale Production of Quality by Design (QbD) Based Nanomedicine

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2:40 p.m. - 3:20 p.m. Joyce Hotz - AstraZeneca

Scale Up of Bydureon

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3:20 p.m. - 3:50 p.m. Networking Break & Poster Viewing
3:50 p.m. - 4:30 p.m. Mark Prausnitz - Georgia Institute of Technology

Microneedle Device for Long-Acting Contraceptive Hormone

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4:30 p.m. - 5:10 p.m. David Friend - Daré Bioscience, Inc.

An Innovative Long-Acting Implant for Contraception

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5:10 p.m. - 5:50 p.m. Charles Flexner - Johns Hopkins University

Novel Approaches to HIV Treatment and Prevention using Long-Acting Drug Delivery

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5:50 p.m. - 6:00 p.m. Day One Closing Remarks
6:00 p.m. - 8:00 p.m. Dinner and Panel Discussion Sponsored by MedinCell and Medicines Patent Pool (Americana Ballroom)

Friday, Feb. 7, 2020

8:00 a.m. - 9:00 a.m. Breakfast
9:00 a.m. - 9:10 a.m. Welcome and Opening Remarks
9:10 a.m. - 9:50 a.m. Tejal Desai - University of California, San Francisco

Nanostructured Materials for Long Acting Biologic Delivery

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9:50 a.m. - 10:30 a.m. Tassos Nicolaou - Delpor

Prozor Technology and the Potential for Once-Yearly Therapies

View Abstract
10:30 a.m. - 11:00 a.m. Networking Break & Poster Viewing
11:00 a.m. - 11:40 a.m. Jon Pokorski - University of California, San Diego

Melt Processing of Functional Protein/Polymer Blends

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11:40 a.m. - 12:20 p.m. Hongwen Rivers - Allergan

To Develop Long-Acting Complex Dosage Forms of Biologics for the Eye: Opportunities and Challenges

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12:20 p.m. - 1:20 p.m. Lunch Sponsored by Lubrizol Life Science (Chronicle Room)
1:20 p.m. - 2:00 p.m. Karsten Mäder - Martin Luther University Halle-Wittenberg

Noninvasive In Vitro and In Vivo Characterization of Biodegradable Parenteral Depot Formulations

View Abstract
2:00 p.m. - 2:40 p.m. Sheng Qi - University of East Anglia

3D Printing of Personalised Long-Acting Pharmaceutical Implants: Conceptual Analysis and Printing Design

View Abstract
2:40 p.m. - 3:00 p.m. Networking Break & Poster Viewing
3:00 p.m. - 3:40 p.m. Wim Jiskoot - Leiden University

Long-Acting Injectables & Implantables: Immunogenicity Concerns

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3:40 p.m. - 4:20 p.m. Omid Veiseh - William Marsh Rice University

Immune Modulatory Biomaterials for Cell-Based Therapeutics

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4:20 p.m. - 4:40 p.m. Networking Break & Poster Viewing
4:40 p.m. - 5:20 p.m. Steve Schwendeman - University of Michigan

A Cage Implant to Study Drug Release from Microspheres In Vivo

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5:20 p.m. - 6:00 p.m. Viera Lukacova - Simulations Plus, Inc.

What Does it Take to Develop a PBPK Model that Mimics In Vivo Behavior of LAIs

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6:00 p.m. - 6:40 p.m. Diane Burgess - University of Connecticut

Development of IVIVCs for Complex Parenteral Products

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6:40 p.m. - 6:50 p.m. Day Two Closing Remarks

Sponsored Programming

Thursday Lunch | Sponsored by Celanese

12:20 p.m. – 1:20 p.m.

Jeff Haley – Celanese Engineered Materials

Ethylene-Vinyl Acetate Polymers for Long-Acting Dosage Forms

View Abstract

Friday Lunch | Sponsored by Lubrizol Life Science

12:20 p.m. – 1:20 p.m.

Robert Lee – Lubrizol Life Science

Overcoming Development Challenges for Long-Acting Injectables & Implantables
View Abstract

Thursday Dinner and Global Health Panel Discussion | Sponsored by MedinCell & Medicines Patent Pool


6:30 p.m. – 8:30 p.m.

  • Charles Flexner (chair) – Long-Acting/Extended Release Antiretroviral Resource Program (LEAP)
  • Carmen Pérez CasasUnitaid
  • Dennis LeeThe Bill & Melinda Gates Foundation
  • Andrew OwenUniversity of Liverpool
  • Rodney HoUniversity of Washington
  • Stephanie BarrettMerck
  • Christophe RobergeMedinCell
  • Esteban BurroneMedicines Patent Pool

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Thank You To Our LAII 2020 Sponsors

Gold-Level Sponsors

Silver-Level Sponsor

Exhibiting Sponsors

Sponsorship Opportunities

LAII 2021 offers several sponsorship packages for companies looking for access to our attendees and unique brand exposure. For more information on sponsorship opportunities for next year’s meeting, please connect laii@ddelabs.com.

Thank You to the 2020 Planning Committee

Nima Akhavein, GSK
Maria Josè Alonso, USC
Rene Holm, Janssen
Julius Korley, University of Delaware
Laxma Reddy, Drug Delivery Experts
Chris Rhodes, Drug Delivery Experts
Steve Schwendeman, University of Michigan
An Vermeulen, Janssen
Dennis Lee, Gates Foundation

LAII 2020 Accepted Poster Presentations


Self-Administered Biodegradable Microneedle Patches for Sustained Release of Etonogestrel

By: Derek Jang+, Jonathan Chen+, Jie Tang, Richard Terry, Steve Schwendeman, Mark R. Prausnitz (Georgia Institute of Technology)

 

Probing Particle-Stabilizer Interactions in Long-Acting Parenteral Formulations through Novel In Vitro Methods and Spectroscopic Techniques

By: Nathan Rudd (Merck & Co., Inc.)

 

Noninvasive Replenishment of Drug Depots In Vivo

By: Yevgeny Brudno (UNC – Chapel Hill and NC State – Raleigh)

 

GQDs and MnFe2O3 Decorated Molybdenum Nanosheets for sub cellular Targeted Dual Mode Photodynamic Therapy (PDT)/Photothermal Therapy (PTT) of Glioblastoma

By: Abhijeet Pandey (Manipal College of Pharmaceutical Sciences)

 

Long-Acting Implantables Using Surface-eroding Elastomers Sustain Zero-order, Multi-month release

By: Stephanie Reed (Secant)

 

Micro-imaging Based Characterization and Prediction of Long-Acting Parenteral

By: Shawn Zhang (DigiM), Karthik Nagapudi (Genentech)

 

Novel Long-Acting Injectable Photocrosslinked Drug Delivery Systems for the Treatment of Ocular Diseases

By: Raj Thakur (Re-Vana Therapeutics)

Presentation & Poster Abstract Submission for LAII 2021

We are currently accepting presentation & poster abstracts for next year's meeting. Please leave your name, email, your talk/poster title, and abstract below: