Equipment

Characterization

High Performance Liquid Chromatography (HPLC) with Diode Array, ELSD, and Fluorescence detectors for formulation characterization, in vitro release and stability, and polymer molecular weight

Ultraviolet-visible and Fluorescence Absorbance Spectroscopy Plate Readers for concentration determination, plasma compatibility and solubility screening

Particle Size Determination by Laser Diffraction and Dynamic Light Scattering

Osmometer and Viscometer

Instron Force Tester for force and brake force testing for component compatibility

High Performance Liquid Chromatography with Tandem Mass Spectroscopy (LCMSMS) for molecular weight determination and bioanalysis

Scanning Electron Microscope (SEM) for morphology, particle size, and crystallinity

Light Microscopy

Protein Characterization and Purification

Gel Electrophoresis Imager for imaging protein gels

Fast Protein Liquid Chromatography (FPLC) for protein purification

Dynamic Light Scattering for determination of hydrodynamic radii estimation

Formulation Process Manufacturing

Laminar Flow-hood for sterile manufacturing

Dehydrogenation Oven and Autoclave for sterile manufacturing

Extruder for particle size reduction and liposome production

Microfluidizer and Ball Mill for particle size reduction

Filtration Skid for pressured filtration at >1L

Tray Lyophilizer

Homogenizer and Probe Sonication for particle size reduction and microsphere production

Stability Chambers for evaluation formulation and API stability and container closure evaluation